TargetMol

GSK 3008348 hydrochloride

Product Code:
 
TAR-T15583
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T15583-5mg5mg£1,347.00
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Further Information

Bioactivity:
GSK 3008348 hydrochloride is an integrin αvβ6 antagonist. The affinity (pIC50) for the human - a 6 protein in the Fluorescence Polarisation Assay for GSK 3008348 is 8.1, whereas its affinity in the cell Adhesion Assays was for α?β6 (pIC50: 8.4); α?β3 (pIC50: 6); α?β5 (pIC50: 6.9); α?β8 (pIC50: 7.7).
CAS:
1629249-40-6
Formula:
C29H37N5O2.xHCl
Molecular Weight:
0
Purity:
0.98
SMILES:
O=C(O)C[C@@H](C1=CC(N2N=C(C)C=C2C)=CC=C1)CN3C[C@H](CCC(N4)=CC=C5C4=NCCC5)CC3.[x].Cl

References

1. Anderson Niall Andrew, et al. Preparation of naphthyridine derivatives useful as ?v?6 integrin antagonists. From PCT Int. Appl. (2014), WO 2014154725 A1 20141002.