TargetMol

IRL-1620

Product Code:
 
TAR-T15595
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T15595-5mg5mg£850.00
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Further Information

Bioactivity:
IRL-1620 is an effective and selective agonist of endothelin receptor type B (ETB) (Ki: 16 pM).
CAS:
142569-99-1
Formula:
C86H117N17O27
Molecular Weight:
1820.95
Purity:
0.98
SMILES:
0

References

1. Takai M, et al. A potent and specific agonist, Suc-[Glu9,Ala11,15]-endothelin-1(8-21), IRL 1620, for the ETB receptor. Biochem Biophys Res Commun. 1992 Apr 30;184(2):953-9. 2. Briyal S, et al. Stimulation of endothelin B receptors by IRL-1620 decreases the progression of Alzheimer's disease. Neuroscience. 2015 Aug 20;301:1-11. 3. Gulati S, et al. Attenuation of opioid tolerance by ETB receptor agonist, IRL-1620, is independent of an accompanied decrease in nerve growth factor in mice. Heliyon. 2017 Jun 7;3(6):e00317.