TargetMol

KU 59403

Product Code:
 
TAR-T15673
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1

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CodeSizePrice
TAR-T15673-5mg5mg£302.00
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TAR-T15673-50mg50mg£1,010.00
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TAR-T15673-100mg100mg£1,492.00
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
KU 59403 is an effective ATM inhibitor (IC50: 3 nM, 9.1 μM, and 10 μM for ATM, DNA-PK, and PI3K, respectively).
CAS:
845932-30-1
Formula:
C29H32N4O4S2
Molecular Weight:
564.72
Pathway:
DNA Damage/DNA Repair; PI3K/Akt/mTOR signaling
Purity:
0.98
SMILES:
CN1CCN(CCC(=O)Nc2ccc3Sc4c(Sc3c2)cccc4-c2cc(=O)cc(o2)N2CCOCC2)CC1
Target:
ATM/ATR

References

1. Batey MA, et al. Preclinical evaluation of a novel ATM inhibitor, KU59403, in vitro and in vivo in p53 functional and dysfunctional models of human cancer. Mol Cancer Ther. 2013 Jun;12(6):959-67.