TargetMol

Latanoprost acid

Product Code:
 
TAR-T15718
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T15718-1mg1mg£140.00
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Quantity:
TAR-T15718-1mL1 mL * 10 mM (in DMSO)£362.00
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TAR-T15718-5mg5mg£373.00
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TAR-T15718-10mg10mg£516.00
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TAR-T15718-25mg25mg£772.00
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Quantity:
TAR-T15718-50mg50mg£1,018.00
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Quantity:
TAR-T15718-100mg100mg£1,372.00
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Quantity:
TAR-T15718-500mg500mg£2,665.00
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Quantity:
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This product comes from: United States.
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Further Information

Bioactivity:
Latanoprost acid is a prostanoid receptor agonist that specifically activates the FP-PG receptor. It inhibits RANKL-induced osteoclastgenesis and function by inhibiting ERK, AKT, JNK, and p38 cascade, following by the c-fos/NFATc1 pathway. Latanoprost acid works to lower pressure inside the eyes.
CAS:
41639-83-2
Formula:
C23H34O5
Molecular Weight:
390.52
Pathway:
Endocrinology/Hormones|GPCR/G Protein
Purity:
0.98
SMILES:
O[C@H](CC[C@H]1[C@H](O)C[C@H](O)[C@@H]1CC=C/CCCC(O)=O)CCc1ccccc1
Target:
GPR

References

1. Weinreb RN, et al. Effects of prostaglandins on the aqueous humor outflow pathways. Surv Ophthalmol. 2002 Aug;47 Suppl 1:S53-64. 2. Xu X, et al. The prevention of latanoprost on osteoclastgenesis in vitro and lipopolysaccharide-induced murine calvaria osteolysis in vivo. J Cell Biochem. 2018 Jun;119(6):4680-4691.