TargetMol

Lexibulin dihydrochloride

Product Code:
 
TAR-T15746
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T15746-5mg5mg£850.00
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TAR-T15746-50mg50mg£1,661.00
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Quantity:
TAR-T15746-100mg100mg£2,079.00
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This product comes from: United States.
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Further Information

Bioactivity:
Lexibulin 2Hcl is an effective tubulin polymerization inhibitor (IC50: 10-100 nM in cancer cell lines). It also has potent cytotoxic and vascular disrupting activity in vitro and in vivo.
CAS:
917111-49-0
Formula:
C24H32Cl2N6O2
Molecular Weight:
507.46
Purity:
0.98
SMILES:
Cl.Cl.CCC[C@H](Nc1nc(ncc1C)-c1ccc(NC(=O)NCC)c(OC)c1)c1cccnc1

References

1. Burns CJ, et al. CYT997: a novel orally active tubulin polymerization inhibitor with potent cytotoxic and vascular disrupting activity in vitro and in vivo. Mol Cancer Ther. 2009 Nov;8(11):3036-45. 2. Monaghan K, et al. CYT997 causes apoptosis in human multiple myeloma. Invest New Drugs. 2011 Apr;29(2):232-8.