TargetMol

LTURM34

Product Code:
 
TAR-T15789
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T15789-5mg5mg£122.00
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Quantity:
TAR-T15789-1mL1 mL * 10 mM (in DMSO)£127.00
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TAR-T15789-10mg10mg£161.00
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TAR-T15789-25mg25mg£269.00
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TAR-T15789-50mg50mg£414.00
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Quantity:
TAR-T15789-100mg100mg£584.00
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This product comes from: United States.
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Further Information

Bioactivity:
LTURM34 is an inhibitor of DNA-PK with IC50 of 34 nM. LTURM34 displays effective antiproliferative activity in a wide range of tumor cell lines. LTURM34 shows 170-fold selectivity for DNA-PK over PI3K .
CAS:
1879887-96-3
Formula:
C24H18N2O3S
Molecular Weight:
414.48
Pathway:
PI3K/Akt/mTOR signaling; DNA Damage/DNA Repair
Purity:
0.9991
SMILES:
O=c1nc(oc2c(cccc12)-c1cccc2c3ccccc3sc12)N1CCOCC1
Target:
DNA-PK; PI3K; PI4K

References

1. Morrison R, et al. Synthesis, structure elucidation, DNA-PK and PI3K and anti-cancer activity of 8- and 6-aryl-substituted-1-3-benzoxazines. Eur J Med Chem. 2016 Mar 3;110:326-39.