TargetMol

NMS-P515

Product Code:
 
TAR-T16334
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T16334-5mg5mg£390.00
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TAR-T16334-50mg50mg£1,444.00
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Quantity:
TAR-T16334-100mg100mg£2,151.00
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
NMS-P515 is an effective, orally active, and stereospecific PARP-1 inhibitor (Kd: 16 nM and an IC50: 27 nM (in Hela cells)). It has anti-tumor activity.
CAS:
1262395-13-0
Formula:
C21H29N3O2
Molecular Weight:
355.482
Purity:
0.98
SMILES:
C[C@@H]1N(C2CCN(CC2)C2CCCCC2)C(=O)c2c1cccc2C(N)=O

References

1. Papeo G, et al. Discovery of Stereospecific PARP-1 Inhibitor Isoindolinone NMS-P515. ACS Med Chem Lett. 2019 Mar 13;10(4):534-538.