TargetMol

Tenofovir

Product Code:
 
TAR-T1649
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T1649-1mL1 mL * 10 mM (in DMSO)£111.00
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TAR-T1649-10mg10mg£111.00
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TAR-T1649-25mg25mg£128.00
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TAR-T1649-50mg50mg£147.00
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TAR-T1649-100mg100mg£179.00
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TAR-T1649-500mg500mg£355.00
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This product comes from: United States.
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Further Information

Bioactivity:
Tenofovir is an adenine analog REVERSE TRANSCRIPTASE INHIBITOR with antiviral activity against HIV-1 and HEPATITIS B. It is used to treat HIV INFECTIONS and CHRONIC HEPATITIS B, in combination with other ANTIVIRAL AGENTS, due to the emergence of ANTIVIRAL DRUG RESISTANCE when it is used alone.
CAS:
147127-20-6
Formula:
C9H14N5O4P
Molecular Weight:
287.21
Pathway:
Proteases/Proteasome; Microbiology/Virology
Purity:
0.9983
SMILES:
n1(c2c(nc1)c(ncn2)N)C[C@H](OCP(=O)(O)O)C
Target:
HBV; HIV Protease; Reverse Transcriptase

References

1. Witvrouw M, et al. Antivir Ther, 2004, 9(1), 57-65. 2. Miller MD, et al. Nucleosides Nucleotides Nucleic Acids, 2001, 20(4-7), 1025-1028. 3. Ying C, et al. J Viral Hepat, 2000, 7(2), 161-165. 4. Wainberg MA, et al. Antivir Ther, 1999, 4(2), 87-94. 5. De Clercq E, et al. Clin Microbiol Rev, 2003, 16(4), 569-596. 6. Musumeci G, et al. M48U1 and Tenofovir combination synergistically inhibits HIV infection in activated PBMCs and human cervicovaginal histocultures. Sci Rep. 2017 Feb 1;7:41018. 7. Wu Y, Yang J, Duan C, et al. Simultaneous determination of antiretroviral drugs in human hair with liquid chromatography-electrospray ionization-tandem mass spectrometry[J]. Journal of Chromatography B. 2018 Apr 15;1083:209-221. 8. Tan S, Li W, Li Z, et al. A Novel CXCR4 Targeting Protein SDF-1/54 as an HIV-1 Entry Inhibitor. Viruses. 2019, 11(9): 874.