TargetMol

Psicofuranine

Product Code:
 
TAR-T16677
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T16677-5mg5mg£722.00
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Further Information

Bioactivity:
Psicofuranine also specifically inhibits GMP synthase and interrupts parasite growth. Psicofuramine is a nucleoside antibiotic. It has the inhibition of xanthosine 5'-phosphate aminase. Psicofuranine shows dose-dependent inhibition of P. falciparum growth(IC50: 0.3 mM).
CAS:
1874-54-0
Formula:
C11H15N5O5
Molecular Weight:
297.271
Purity:
0.98
SMILES:
Nc1ncnc2n(cnc12)[C@]1(CO)O[C@H](CO)[C@@H](O)[C@H]1O

References

1. cConkey GA. Plasmodium falciparum: isolation and characterisation of a gene encoding protozoan GMP synthase. Exp Parasitol. 2000 Jan;94(1):23-32. 2. UDAKA S, et al. INHIBITION OF PARENTAL AND MUTANT XANTHOSINE 5'-PHOSPHATE AMINASES BY PSICOFURANINE. J Biol Chem. 1963 Aug;238:2797-803.