TargetMol

QCA570

Product Code:
 
TAR-T16701
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T16701-5mg5mg£1,299.00
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TAR-T16701-50mg50mg£3,589.00
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Quantity:
TAR-T16701-100mg100mg£4,970.00
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This product comes from: United States.
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Further Information

Bioactivity:
QCA570 is an effective BET degrader based on PROTAC (IC50: 10 nM for BRD4 BD1 Protein).
CAS:
2207569-08-0
Formula:
C39H33N7O4S
Molecular Weight:
695.8
Purity:
0.98
SMILES:
Cc1nnc2COCc3c(Cc4ccccc4)c(sc3-n12)C#Cc1cnn(CCCC#Cc2cccc3C(=O)N(Cc23)C2CCC(=O)NC2=O)c1

References

1. Qin C, et al. Discovery of QCA570 as an Exceptionally Potent and Efficacious Proteolysis Targeting Chimera (PROTAC) Degrader of the Bromodomain and Extra-Terminal (BET) Proteins Capable of Inducing Complete and Durable Tumor Regression. J Med Chem. 2018 Aug 9;61(15):6685-6704.