TargetMol

S-2474

Product Code:
 
TAR-T16817
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T16817-5mg5mg£850.00
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Quantity:
TAR-T16817-50mg50mg£1,661.00
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Quantity:
TAR-T16817-100mg100mg£2,079.00
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This product comes from: United States.
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Further Information

Bioactivity:
S-2474 is an inhibitor of COX-2 and 5-lipoxygenase (IC50s: 11 nM and 27 μM for COX-2 and COX-1 in human intact cells).
CAS:
158089-95-3
Formula:
C20H31NO3S
Molecular Weight:
365.53
Pathway:
Neuroscience; Immunology/Inflammation
Purity:
0.98
SMILES:
CCN1CCC(=C/c2cc(c(O)c(c2)C(C)(C)C)C(C)(C)C)S1(=O)=O
Target:
COX

References

1. Yagami T, et al. Effects of S-2474, a novel nonsteroidal anti-inflammatory drug, on amyloid beta protein-induced neuronal cell death. Br J Pharmacol. 2001 Oct;134(3):673-81. 2. Yagami T, et al. S-2474, a novel nonsteroidal anti-inflammatory drug, rescues cortical neurons from human group IIA secretory phospholipase A(2)-induced apoptosis. Neuropharmacology. 2005 Aug;49(2):174-84. Epub 2005 Apr 1.