TargetMol

SB-568849

Product Code:
 
TAR-T16852
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T16852-5mg5mg£930.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T16852-50mg50mg£1,821.00
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Quantity:
TAR-T16852-100mg100mg£2,319.00
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
SB-568849 is a melanin-concentrating hormone receptor 1 antagonist (pKi: 7.7).
CAS:
395679-53-5
Formula:
C28H31F3N2O3
Molecular Weight:
500.562
Purity:
0.98
SMILES:
CCN(CC)CCOc1ccc(cc1OC)N(C)C(=O)c1ccc(cc1)-c1ccc(cc1)C(F)(F)F

References

1. Witty DR, et al. Discovery of potent and stable conformationally constrained analogues of the MCH R1 antagonist SB-568849. Bioorg Med Chem Lett. 2006 Sep 15;16(18):4872-8. 2. Kennedy AR, et al. Effect of direct injection of melanin-concentrating hormone into the paraventricular nucleus: further evidence for a stimulatory role in the adrenal axis via SLC-1. J Neuroendocrinol. 2003 Mar;15(3):268-72. 3. Witty DR, et al. SAR of biphenyl carboxamide ligands of the human melanin-concentrating hormone receptor 1 (MCH R1): discovery of antagonist SB-568849. Bioorg Med Chem Lett. 2006 Sep 15;16(18):4865-71.