TargetMol

U-46619

Product Code:
 
TAR-T17189
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T17189-1mg1mg£464.00
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TAR-T17189-5mg5mg£1,089.00
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This product comes from: United States.
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Further Information

Bioactivity:
U-46619 is a stable analog of thromboxane A2 and acts as an effective TXA2 agonist.
CAS:
56985-40-1
Formula:
C21H34O4
Molecular Weight:
350.499
Pathway:
DNA Damage/DNA Repair|Others|Metabolism
Purity:
0.98
SMILES:
[H][C@]12CO[C@]([H])(C1)[C@H](C=C[C@@H](O)CCCCC)[C@H]2CC=C/CCCC(O)=O
Target:
Progesterone Receptor|PPAR

References

Su L, et al. The prostaglandin H2 analog U-46619 improves the differentiation efficiency of human induced pluripotent stem cells into endothelial cells by activating both p38MAPK and ERK1/2 signaling pathways. Stem Cell Res Ther. 2018;9(1):313. Schirner M, et al. U 46619 induces different blood pressure effects in male and female spontaneously hypertensive rats (SHR). Prostaglandins Leukot Essent Fatty Acids. 1993;48(6):469-473. Ohkubo S,et al. Thromboxane A2-mediated shape change: independent of Gq-phospholipase C--Ca2+ pathway in rabbit platelets. Br J Pharmacol. 1996;117(6):1095-1104.