TargetMol

Phenylephrine

Product Code:
 
TAR-T17310
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T17310-500mg500mg£104.00
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Quantity:
TAR-T17310-1mL1 mL * 10 mM (in DMSO)£107.00
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Further Information

Bioactivity:
Phenylephrine is a selective α1-adrenoceptor agonist ( pKi: 5.86, 4.87 and 4.70 for α1D, α1B, and α1A receptors respectively).
CAS:
59-42-7
Formula:
C9H13NO2
Molecular Weight:
167.208
Pathway:
Neuroscience; GPCR/G Protein
Purity:
0.9992
SMILES:
CNC[C@H](O)c1cccc(O)c1
Target:
Adrenergic Receptor

References

1. Ford AP, et al. Pharmacological pleiotropism of the human recombinant alpha1A-adrenoceptor: implications foralpha1-adrenoceptor classification. Br J Pharmacol. 1997 Jul;121(6):1127-35. 2. Minneman KP, et al. Selectivity of agonists for cloned alpha 1-adrenergic receptor subtypes. Mol Pharmacol. 1994 Nov;46(5):929-36. 3. Wang J, et al. Phenylephrine promotes cardiac fibroblast proliferation through calcineurin-NFAT pathway. Front Biosci (Landmark Ed). 2016 Jan 1;21:502-13. 4. Lazou A, et al. Activation of mitogen-activated protein kinases (p38-MAPKs, SAPKs/JNKs and ERKs) by the G-protein-coupled receptor agonist phenylephrine in the perfused rat heart. Biochem J. 1998 Jun 1;332 ( Pt 2):459-65. 5. Li NJ, et al. Effect of phenylephrine on alveolar fluid clearance in ventilator-induced lung injury. Chin Med Sci J. 2013 Mar;28(1):1-6. 6. Chen F, Xu Y, Wang J, et al. Relaxation Effect of Patchouli Alcohol in Rat Corpus Cavernous and Its Underlying Mechanisms[J]. Evidence-Based Complementary and Alternative Medicine. 2020, 2020.