TargetMol

E3 ligase Ligand 8

Product Code:
 
TAR-T17879
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T17879-5mg5mg£99.00
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Quantity:
TAR-T17879-10mg10mg£115.00
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Quantity:
TAR-T17879-25mg25mg£161.00
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TAR-T17879-50mg50mg£222.00
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Quantity:
TAR-T17879-100mg100mg£322.00
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Quantity:
TAR-T17879-500mg500mg£687.00
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Quantity:
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Further Information

Bioactivity:
E3 ligase Ligand 8 is a ligand for E3 ubiquitin ligase. The E3 ligase Ligand 8 can be linked to protein ligands through linkers to form PROTACs, which are inducers of ubiquitination-mediated degradation of cancer-promoting proteins.
CAS:
1225383-33-4
Formula:
C31H34N2O6
Molecular Weight:
530.621
Pathway:
PROTAC|Others
Purity:
0.9886
SMILES:
CC(C)C[C@H](NC(=O)[C@@H](O)[C@@H](Cc1ccccc1)NC(=O)OCC1c2ccccc2-c2ccccc12)C(O)=O
Target:
Ligand for E3 Ligase|Others

References

1. Shibata N, et al. Development of Protein Degradation Inducers of Androgen Receptor by Conjugation of Androgen Receptor Ligands and Inhibitor of Apoptosis Protein Ligands. J Med Chem. 2018 Jan 25;61(2):543-575.