TargetMol

Fosaprepitant dimeglumine

Product Code:
 
TAR-T1790
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T1790-5mg5mg£107.00
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TAR-T1790-10mg10mg£119.00
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TAR-T1790-1mL1 mL * 10 mM (in DMSO)£127.00
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TAR-T1790-25mg25mg£169.00
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TAR-T1790-50mg50mg£250.00
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TAR-T1790-100mg100mg£367.00
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This product comes from: United States.
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Further Information

Bioactivity:
Fosaprepitant Dimeglumine is the dimeglumine salt form of fosaprepitant, the water-soluble, N-phosphorylated prodrug of aprepitant, with antiemetic activity. Upon intravenous administration and rapid conversion to aprepitant, this agent binds selectively to the human substance P/neurokinin 1 (NK1) receptors in the central nervous system (CNS). This inhibits receptor binding of the endogenous substance P and prevents substance P-induced emesis.
CAS:
265121-04-8
Formula:
C37H56F7N6O16P
Molecular Weight:
1004.844
Pathway:
GPCR/G Protein; Neuroscience
Purity:
0.9875
SMILES:
CNC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO.CNC[C@H](O)[C@@H](O)[C@H](O)[C@H](O)CO.C[C@@H](O[C@H]1OCCN(Cc2nn(c(=O)[nH]2)P(O)(O)=O)[C@H]1c1ccc(F)cc1)c1cc(cc(c1)C(F)(F)F)C(F)(F)F
Target:
Neurokinin receptor

References

1. Navari RM. Expert Opin Investig Drugs, 2007, 16(12), 1977-1985.