TargetMol

(S,R,S)-AHPC-PEG2-NH2 hydrochloride

Product Code:
 
TAR-T17924
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T17924-5mg5mg£98.00
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TAR-T17924-1mL1 mL * 10 mM (in DMSO)£115.00
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TAR-T17924-10mg10mg£115.00
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TAR-T17924-25mg25mg£161.00
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TAR-T17924-50mg50mg£213.00
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TAR-T17924-100mg100mg£275.00
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Quantity:
TAR-T17924-500mg500mg£584.00
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Further Information

Bioactivity:
(S,R,S)-AHPC-PEG2-NH2 hydrochloride (VH032-PEG2-NH2 hydrochloride) is a synthesized E3 ligase ligand-linker conjugate. (S,R,S)-AHPC-PEG2-NH2 hydrochloride incorporates the (S,R,S)-AHPC based VHL ligand and 2-unit PEG linker used in the synthesis of PROTAC.
CAS:
2097973-72-1
Formula:
C28H42ClN5O6S
Molecular Weight:
612.18
Pathway:
PROTAC|Others
Purity:
0.9781
SMILES:
O=C([C@H]1N(C([C@@H](NC(COCCOCCN)=O)C(C)(C)C)=O)C[C@H](O)C1)NCC2=CC=C(C3=C(C)N=CS3)C=C2.[H]Cl
Target:
Others|E3 Ligase Ligand-Linker Conjugate

References

1. Chan KH, et al. Impact of Target Warhead and Linkage Vector on Inducing Protein Degradation: Comparison of Bromodomain and Extra-Terminal (BET) Degraders Derived from Triazolodiazepine (JQ1) and Tetrahydroquinoline (I-BET726) BET Inhibitor Scaffolds. J Med Chem. 2018 Jan 25;61(2):504-513.