TargetMol

GW788388

Product Code:
 
TAR-T1800
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T1800-5mg5mg£117.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T1800-1mL1 mL * 10 mM (in DMSO)£118.00
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Quantity:
TAR-T1800-10mg10mg£148.00
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TAR-T1800-25mg25mg£209.00
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Quantity:
TAR-T1800-50mg50mg£296.00
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Quantity:
TAR-T1800-100mg100mg£402.00
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Quantity:
TAR-T1800-500mg500mg£844.00
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Quantity:
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This product comes from: United States.
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Further Information

Bioactivity:
GW788388 is a potent and selective inhibitor of ALK5, also inhibits TGF-(beta) type II receptor and activin type II receptor activities.
CAS:
452342-67-5
Formula:
C25H23N5O2
Molecular Weight:
425.492
Pathway:
Stem Cells; Tyrosine Kinase/Adaptors; Angiogenesis
Purity:
0.98
SMILES:
O=C(NC1CCOCC1)c1ccc(cc1)-c1cc(ccn1)-c1c[nH]nc1-c1ccccn1
Target:
ALK; TGF-beta/Smad

References

1. Gellibert F, et al. J Med Chem. 2006, 49(7), 2210-2221. 2. Petersen M, et al. Kidney Int, 2008, 73(6), 705-715. 3. Tan SM, et al. Am J Physiol Heart Circ Physiol, 2010, 298(5), H1415-1425. 4. Lagares D, et al. Arthritis Rheum, 2010, 62(3), 878-889.