TargetMol

DL-threo-2-methylisocitrate

Product Code:
 
TAR-T19292
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T19292-5mg5mg£850.00
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TAR-T19292-50mg50mg£1,661.00
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Quantity:
TAR-T19292-100mg100mg£2,079.00
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This product comes from: United States.
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Further Information

Bioactivity:
dl-threo-2-methylisocitrate is a substrate of isocitrate lyase 1 (ICL1). IC50 value: target: using michael-menten nonlinear least squares fitting to determine the purified recombinant ICL1's Km for threo-D(s)L(s)-isocitrate (ICA) is 188?M and kcat is 5.24 s- 1. The Km of DL-threo-2-methylisocitrate (MICA) is about 4 times that of 718, and the kcat is 1.25 s-1.
CAS:
71183-66-9
Formula:
C14H20O14
Molecular Weight:
412.3
Purity:
0.98
SMILES:
[H][C@](CC(O)=O)(C(O)=O)[C@](C)(O)C(O)=O.[H][C@@](CC(O)=O)(C(O)=O)[C@@](C)(O)C(O)=O

References

1. Gould TA, et al. Dual role of isocitrate lyase 1 in the glyoxylate and methylcitrate cycles in Mycobacterium tuberculosis. Mol Microbiol. 2006 Aug;61(4):940-7.