TargetMol

B-AP15

Product Code:
 
TAR-T1932
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T1932-5mg5mg£96.00
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Quantity:
TAR-T1932-1mL1 mL * 10 mM (in DMSO)£106.00
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Quantity:
TAR-T1932-10mg10mg£112.00
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Quantity:
TAR-T1932-25mg25mg£142.00
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TAR-T1932-50mg50mg£177.00
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Quantity:
TAR-T1932-100mg100mg£251.00
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Quantity:
TAR-T1932-200mg200mg£389.00
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Quantity:
TAR-T1932-500mg500mg£613.00
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Quantity:
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
B-AP15(NSC687852) is a selective inhibitor of the deubiquitinating enzymes Usp14 and UCHL5 of the 26S proteasome. It blocks the deubiquitinating activity of the 26S proteasome.
CAS:
1009817-63-3
Formula:
C22H17N3O6
Molecular Weight:
419.393
Pathway:
DNA Damage/DNA Repair; Apoptosis; Cell Cycle/Checkpoint; Ubiquitination
Purity:
0.98
SMILES:
[O-][N+](=O)c1ccc(C=C2/CN(CC(=C/c3ccc(cc3)[N+]([O-])=O)C2=O)C(=O)C=C)cc1
Target:
Apoptosis; DUB

References

1. D'Arcy P, et al. Nat Med. 2011, 17(12):1636-40. 2. D'Arcy P, et al. Int J Biochem Cell Biol. 2012, 44(11):1729-38. 3. Lopez-Castejon G, et al. J Biol Chem, 2013, 288(4), 2721-2733.