TargetMol

FR 180204

Product Code:
 
TAR-T1956
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T1956-1mg1mg£99.00
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TAR-T1956-2mg2mg£111.00
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TAR-T1956-5mg5mg£133.00
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TAR-T1956-1mL1 mL * 10 mM (in DMSO)£140.00
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TAR-T1956-10mg10mg£183.00
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TAR-T1956-25mg25mg£258.00
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TAR-T1956-50mg50mg£351.00
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Quantity:
TAR-T1956-100mg100mg£491.00
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This product comes from: United States.
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Further Information

Bioactivity:
FR180204 is a potent and selective ATP-competitive inhibitor of ERK1 and ERK2.
CAS:
865362-74-9
Formula:
C18H13N7
Molecular Weight:
327.351
Pathway:
Apoptosis; MAPK
Purity:
0.998
SMILES:
Nc1n[nH]c2nnc(cc12)-c1c(nn2ccccc12)-c1ccccc1
Target:
Apoptosis; ERK

References

1. Ohori M, et al. Biochem Biophys Res Commun. 2005, 336(1), 357-363. 2. Ohori M, et al. Naunyn Schmiedebergs Arch Pharmacol. 2007, 374(4), 311-316. 3. Honda M, et al. Cell Physiol Biochem. 2012, 29(5-6), 667-674. 4. Sreekanth GP, et al. Virus Res. 2014, 188, 15-26. 5. Lv, Jiawen, Junchao Zeng, Wen Zhao, Yuanxiong Cheng, Lin Zhang, Shaoxi Cai, Guodong Hu, and Yinghua Chen. Cdc42 regulates LPS-induced proliferation of primary pulmonary microvascular endothelial cells via ERK pathway [J]. Microvascular research . 2017 Jan;109:45-53 6. Lin H, Lu P, Zhou M, et al. Purification of recombinant human fibroblast growth factor 13 in E. coli and its molecular mechanism of mitogenesis[J]. Applied microbiology and biotechnology. 2019: 1-11.