TargetMol

Tiomolibdate diammonium

Product Code:
 
TAR-T19668
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T19668-500mg500mg£129.00
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Further Information

Bioactivity:
Tiomolibdate diammonium is an inhibitor of superoxide dismutase 1 (SOD1) exerting antiangiogenic and antitumor activities. Tiomolibdate diammonium inhibits the activities of cuproenzymes, including SOD1 and COX.
CAS:
15060-55-6
Formula:
H8MoN2S4
Molecular Weight:
260.27
Purity:
0.98
SMILES:
[NH4+].[NH4+].[S-][Mo]([S-])(=S)=S

References

1. Chisholm CL, et al. Ammonium tetrathiomolybdate treatment targets the copper transporter ATP7A and enhances sensitivity of breast cancer to cisplatin. Oncotarget. 2016 Oct 31. 2. Xu S, et al. Ammonium tetrathiomolybdate as a water-soluble and slow-release hydrogen sulfide donor. Bioorg Med Chem Lett. 2016 Mar 15;26(6):1585-8. 3. Chan CM, et al. Pharmacologic evaluation of ammonium tetrathiomolybdate after intravenous and oral administration to healthy dogs. Am J Vet Res. 2015 May;76(5):445-53. 4. Chatterjee S, et al. Ammonium tetrathiomolybdate: a versatile catalyst for hydrogen evolution reaction from water under ambient and hostile conditions. Inorg Chem. 2013 Dec 16;52(24):14168-77.