TargetMol

Aniline mustard

Product Code:
 
TAR-T19736
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T19736-5mg5mg£111.00
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TAR-T19736-1mL1 mL * 10 mM (in DMSO)£118.00
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TAR-T19736-10mg10mg£131.00
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TAR-T19736-25mg25mg£173.00
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TAR-T19736-50mg50mg£225.00
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TAR-T19736-100mg100mg£301.00
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TAR-T19736-200mg200mg£417.00
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TAR-T19736-500mg500mg£643.00
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This product comes from: United States.
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Further Information

Bioactivity:
Aniline mustard is alkylating mustard with anti-neoplastic activity.
CAS:
553-27-5
Formula:
C10H13Cl2N
Molecular Weight:
218.12
Purity:
0.9954
SMILES:
ClCCN(CCCl)c1ccccc1

References

1. Chen CH, Hu TH, Huang TC, Chen YL, Chen YR, Cheng CC, Chen CT. Delineation of G-Quadruplex Alkylation Sites Mediated by 3,6-Bis(1-methyl-4-vinylpyridinium iodide)carbazole-Aniline Mustard Conjugates. Chemistry. 2015 Nov 23;21(48):17379-90. doi: 10.1002/chem.201502595. Epub 2015 Oct 13. PubMed PMID: 26769627. 2. Fedeles BI, Zhu AY, Young KS, Hillier SM, Proffitt KD, Essigmann JM, Croy RG. Chemical genetics analysis of an aniline mustard anticancer agent reveals complex I of the electron transport chain as a target. J Biol Chem. 2011 Sep 30;286(39):33910-20. doi: 10.1074/jbc.M111.278390. Epub 2011 Aug 10. PubMed PMID: 21832047; PubMed Central PMCID: PMC3190774. 3. Benckhuysen C, Ter Hart HG, Van Dijk PJ. Enhanced cytostatic effectiveness of aniline mustard against 7,12-dimethylbenz[a]anthracene-induced rat mammary tumors during regression in response to ovariectomy. Cancer Treat Rep. 1981 Jul-Aug;65(7-8):567-74. PubMed PMID: 6788369. 4. McClean S, Costelloe C, Denny WA, Searcey M, Wakelin LP. Sequence selectivity, cross-linking efficiency and cytotoxicity of DNA-targeted 4-anilinoquinoline aniline mustards. Anticancer Drug Des. 1999 Jun;14(3):187-204. PubMed PMID: 10500495.