TargetMol

Isometamidium chloride

Product Code:
 
TAR-T19744
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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TAR-T19744-5mg5mg£850.00
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Further Information

Bioactivity:
Isometamidium chloride is an antiprotozoal agent. It is also used in veterinary medicine.
CAS:
34301-55-8
Formula:
C28H26ClN7
Molecular Weight:
496.02
Purity:
0.98
SMILES:
[Cl-].CC[n+]1c(-c2ccccc2)c2cc(ccc2c2ccc(N)cc12)N=NNc1cccc(c1)C(N)=N

References

1. Sahin A, Asencio C, Izotte J, Pillay D, Coustou V, Karembe H, Baltz T. The susceptibility of Trypanosoma congolense and Trypanosoma brucei to isometamidium chloride and its synthetic impurities. Vet Parasitol. 2014 Jul 14;203(3-4):270-5. doi: 10.1016/j.vetpar.2014.04.002. Epub 2014 Apr 13. PubMed PMID: 24836423. 2. Tchamdja E, Kulo AE, Akoda K, Teko-Agbo A, Assoumy AM, Niang EM, Batawui K, Adomefa K, Bankol? AA, Kombiagou K, Hoppenheit A, Clausen PH, Mattioli RC, Peter R, Napier GB, De Deken R, Marcotty T, Van Den Abbeele J, Delespaux V. Drug quality analysis through high performance liquid chromatography of isometamidium chloride hydrochloride and diminazene diaceturate purchased from official and unofficial sources in Northern Togo. Prev Vet Med. 2016 Apr 1;126:151-8. doi: 10.1016/j.prevetmed.2016.02.001. Epub 2016 Feb 4. PubMed PMID: 26907208. 3. Van Den Bossche P, Akoda K, Djagmah B, Marcotty T, De Deken R, Kubi C, Parker A, Van Den Abbeele J. Effect of isometamidium chloride treatment on susceptibility of tsetse flies (Diptera: Glossinidae) to trypanosome infections. J Med Entomol. 2006 May;43(3):564-7. PubMed PMID: 16739416. 4. Sow A, Sidib? I, Bengaly Z, Marcotty T, S?r? M, Diallo A, Vitouley HS, Nebi? RL, Ou?draogo M, Akoda GK, Van den Bossche P, Van Den Abbeele J, De Deken R, Delespaux V. Field detection of resistance to isometamidium chloride and diminazene aceturate in Trypanosoma vivax from the region of the Boucle du Mouhoun in Burkina Faso. Vet Parasitol. 2012 Jun 8;187(1-2):105-11. doi: 10.1016/j.vetpar.2011.12.019. Epub 2011 Dec 23. PubMed PMID: 22264748.