TargetMol

Methyllucidone

Product Code:
 
TAR-T19885
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T19885-5mg5mg£609.00
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TAR-T19885-50mg50mg£1,661.00
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Quantity:
TAR-T19885-100mg100mg£2,079.00
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This product comes from: United States.
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Further Information

Bioactivity:
Methyllucidone is an inhibitor of STAT3 that acts by regulating the expression of the protein tyrosine phosphatase MEG2.
CAS:
19956-54-8
Formula:
C16H14O4
Molecular Weight:
270.284
Purity:
0.98
SMILES:
COC(C=Cc1ccccc1)=C1C(=O)C=C(OC)C1=O

References

1. Jin Y, Kim YH, Park JY, Lee YJ, Oh HM, Choi SK, Han DC, Kwon BM. Methyllucidone inhibits STAT3 activity by regulating the expression of the protein tyrosine phosphatase MEG2 in DU145 prostate carcinoma cells. Bioorg Med Chem Lett. 2018 Mar 1;28(5):853-857. doi: 10.1016/j.bmcl.2018.02.012. Epub 2018 Feb 8. PubMed PMID: 29456111. 2. Cui Y, Wu J, Jung SC, Kim GO, Kyeong Ko R, Lee HJ, Yoo ES, Kang HK, Suk K, Eun SY. Neuroprotective effect of methyl lucidone against microglia-mediated neurotoxicity. Eur J Pharmacol. 2012 Sep 5;690(1-3):4-12. doi: 10.1016/j.ejphar.2012.05.041. Epub 2012 Jun 7. PubMed PMID: 22683871. 3. Oh HM, Choi SK, Lee JM, Lee SK, Kim HY, Han DC, Kim HM, Son KH, Kwon BM. Cyclopentenediones, inhibitors of farnesyl protein transferase and anti-tumor compounds, isolated from the fruit of Lindera erythrocarpa Makino. Bioorg Med Chem. 2005 Nov 15;13(22):6182-7. Epub 2005 Aug 1. PubMed PMID: 16055336.