TargetMol

PF-4708671

Product Code:
 
TAR-T2002
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T2002-5mg5mg£108.00
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TAR-T2002-10mg10mg£127.00
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TAR-T2002-1mL1 mL * 10 mM (in DMSO)£132.00
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TAR-T2002-25mg25mg£161.00
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TAR-T2002-50mg50mg£193.00
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TAR-T2002-100mg100mg£295.00
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This product comes from: United States.
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Further Information

Bioactivity:
PF-4708671 is a cell-permeable inhibitor of p70 ribosomal S6 kinase (S6K1 isoform) .In cell-free assays, PF-4708671 is potent for S6K1(Ki50=20 nM, IC50=160 nM).
CAS:
1255517-76-0
Formula:
C19H21F3N6
Molecular Weight:
390.414
Pathway:
PI3K/Akt/mTOR signaling; Autophagy; MAPK
Purity:
0.9967
SMILES:
CCc1cncnc1N1CCN(Cc2nc3cc(ccc3[nH]2)C(F)(F)F)CC1
Target:
S6 Kinase; Autophagy

References

1. Pearce LR, et al. Biochem J, 2010, 431(2), 245-255.