TargetMol

Novobiocin

Product Code:
 
TAR-T20510
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T20510-1mg1mg£95.00
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TAR-T20510-5mg5mg£117.00
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TAR-T20510-10mg10mg£140.00
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TAR-T20510-25mg25mg£197.00
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TAR-T20510-50mg50mg£260.00
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TAR-T20510-100mg100mg£360.00
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Quantity:
TAR-T20510-500mg500mg£705.00
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This product comes from: United States.
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Further Information

Bioactivity:
Novobiocin, an antibiotic compound derived from Streptomyces niveus, has a chemical structure similar to coumarin. It binds to DNA gyrase and blocks ATPase activity.
CAS:
303-81-1
Formula:
C31H36N2O11
Molecular Weight:
612.632
Pathway:
Microbiology/Virology|DNA Damage/DNA Repair|Metabolism|Apoptosis|Cytoskeletal Signaling
Purity:
0.98
SMILES:
CO[C@@H]1[C@@H](OC(N)=O)[C@@H](O)[C@H](Oc2ccc3c(O)c(NC(=O)c4ccc(O)c(CC=C(C)C)c4)c(=O)oc3c2C)OC1(C)C
Target:
Apoptosis|DNA gyrase|HSP|Antibiotic|Antibacterial|Virus Protease

References

1. Shulman A, Yair Y, Biran D, Sura T, Otto A, Gophna U, Becher D, Hecker M, Ron EZ. The Escherichia coli Type III Secretion System 2 Has a Global Effect on Cell Surface. MBio. 2018 Jul 3;9(4). pii: e01070-18. doi: 10.1128/mBio.01070-18. PubMed PMID: 29970469; PubMed Central PMCID: PMC6030553. 2. Stur?d K, Salvadori G, Junges R, Petersen F. Antibiotics alter the window of competence for natural transformation in streptococci. Mol Oral Microbiol. 2018 Jul 2. doi: 10.1111/omi.12240. [Epub ahead of print] PubMed PMID: 29968346. 3. Tomazi T, de Souza Filho AF, Heinemann MB, Santos MVD. Molecular characterization and antimicrobial susceptibility pattern of Streptococcus agalactiae isolated from clinical mastitis in dairy cattle. PLoS One. 2018 Jun 21;13(6):e0199561. doi: 10.1371/journal.pone.0199561. eCollection 2018. PubMed PMID: 29928042; PubMed Central PMCID: PMC6013152. 4. Wagner HJ, Engesser R, Ermes K, Geraths C, Timmer J, Weber W. Characterization of the synthetic biology-inspired implementation of a materials-based positive feedback loop. Data Brief. 2018 May 18;19:665-677. doi: 10.1016/j.dib.2018.05.074. eCollection 2018 Aug. PubMed PMID: 29900367; PubMed Central PMCID: PMC5997908.