TargetMol

Maclurin

Product Code:
 
TAR-T20578
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T20578-5mg5mg£111.00
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TAR-T20578-1mL1 mL * 10 mM (in DMSO)£117.00
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TAR-T20578-10mg10mg£127.00
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TAR-T20578-25mg25mg£162.00
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TAR-T20578-50mg50mg£205.00
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TAR-T20578-100mg100mg£270.00
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Further Information

Bioactivity:
Maclurin is a phenolic component of mulberry twigs, exerts anti-metastatic effects. Maclurin effectively protects against OH-induced damages to DNA and MSCs and can be used in studies about the prevention of many diseases or MSCs transplantation.
CAS:
519-34-6
Formula:
C13H10O6
Molecular Weight:
262.21
Pathway:
Metabolism; Immunology/Inflammation; NF-κb; oxidation-reduction
Purity:
0.98
SMILES:
O=C(C1=CC=C(O)C(O)=C1)C=2C(O)=CC(O)=CC2O
Target:
Free radical scavengers; Reactive Oxygen Species

References

1. Li X, et al. Maclurin protects against hydroxyl radical-induced damages to mesenchymal stem cells: antioxidant evaluation and mechanistic insight. Chem Biol Interact. 2014 Aug 5;219:221-8. 2. Ku MJ, et al. Maclurin suppresses migration and invasion of human non-small-cell lung cancer cells via anti-oxidative activity and inhibition of the Src/FAK-ERK-?-catenin pathway. Mol Cell Biochem. 2015 Apr;402(1-2):243-52. 3. Lee YJ, Lee SY. Maclurin exerts anti-cancer effects in human osteosarcoma cells via prooxidative activity and modulations of PARP, p38, and ERK signaling. IUBMB Life. 2021 Aug;73(8):1060-1072. 4. Kim J, et al. Protective Effects of Maclurin against Benzo[a]pyrene via Aryl Hydrocarbon Receptor and Nuclear Factor Erythroid 2-Related Factor 2 Targeting. Antioxidants (Basel). 2021 Jul 26;10(8):1189.