TargetMol

Fenarimol

Product Code:
 
TAR-T20677
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T20677-5mg5mg£850.00
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This product comes from: United States.
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Further Information

Bioactivity:
Fenarimol, a pyrimidine-type fungicide, exhibits potent inhibitory activity against BR biosynthesis.
CAS:
60168-88-9
Formula:
C17H12Cl2N2O
Molecular Weight:
331.2
Purity:
0.98
SMILES:
OC(c1ccc(Cl)cc1)(c1cncnc1)c1ccccc1Cl

References

1. Oh K, Matsumoto T, Yamagami A, Hoshi T, Nakano T, Yoshizawa Y. Fenarimol, a Pyrimidine-Type Fungicide, Inhibits Brassinosteroid Biosynthesis. Int J Mol Sci. 2015 Jul 29;16(8):17273-88. doi: 10.3390/ijms160817273. PubMed PMID: 26230686; PubMed Central PMCID: PMC4581192. 2. Park M, Han J, Ko JJ, Lee WS, Yoon TK, Lee K, Bae J. Maternal exposure to fenarimol promotes reproductive performance in mouse offspring. Toxicol Lett. 2011 Sep 10;205(3):241-9. doi: 10.1016/j.toxlet.2011.05.1040. Epub 2011 Jun 22. PubMed PMID: 21722721. 3. Parodi DA, Sjarif J, Chen Y, Allard P. Reproductive toxicity and meiotic dysfunction following exposure to the pesticides Maneb, Diazinon and Fenarimol. Toxicol Res (Camb). 2015 May;4(3):645-654. PubMed PMID: 25984295; PubMed Central PMCID: PMC4433152. 4. Keenan M, Chaplin JH, Alexander PW, Abbott MJ, Best WM, Khong A, Botero A, Perez C, Cornwall S, Thompson RA, White KL, Shackleford DM, Koltun M, Chiu FC, Morizzi J, Ryan E, Campbell M, von Geldern TW, Scandale I, Chatelain E, Charman SA. Two analogues of fenarimol show curative activity in an experimental model of Chagas disease. J Med Chem. 2013 Dec 27;56(24):10158-70. doi: 10.1021/jm401610c. Epub 2013 Dec 4. PubMed PMID: 24304150; PubMed Central PMCID: PMC3884847.