TargetMol

Bisabolene

Product Code:
 
TAR-T20749
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T20749-50mg50mg£111.00
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Further Information

Bioactivity:
Bisabolene is a sesquiterpene extracted from oregano and other aromatic plants. It is a potential anticancer agent and studies have shown that it can induce apoptosis in the A549 cancer cell line.
CAS:
495-62-5
Formula:
C15H24
Molecular Weight:
204.357
Purity:
0.98
SMILES:
CC(C)=CCCC(C)=C1CCC(C)=CC1

References

1. Davies FK, Work VH, Beliaev AS, Posewitz MC. Engineering Limonene and Bisabolene Production in Wild Type and a Glycogen-Deficient Mutant of Synechococcus sp. PCC 7002. Front Bioeng Biotechnol. 2014 Jun 19;2:21. 2. Aschenbrenner AK, Kwon M, Conrad J, Ro DK, Spring O. Identification and characterization of two bisabolene synthases from linear glandular trichomes of sunflower (Helianthus annuus L., Asteraceae). Phytochemistry. 2016 Apr;124:29-37. 3. Jou YJ, Chen CJ, Liu YC, Way TD, Lai CH, Hua CH, Wang CY, Huang SH, Kao JY, Lin CW. Quantitative phosphoproteomic analysis reveals ?-bisabolene inducing p53-mediated apoptosis of human oral squamous cell carcinoma via HDAC2 inhibition and ERK1/2 activation. Proteomics. 2015 Oct;15(19):3296-309. 4. Jou YJ, Hua CH, Lin CS, Wang CY, Wan L, Lin YJ, Huang SH, Lin CW. Anticancer Activity of ?-Bisabolene in Human Neuroblastoma Cells via Induction of p53-Mediated Mitochondrial Apoptosis. Molecules. 2016 May 7;21(5).