TargetMol

Gemeprost

Product Code:
 
TAR-T20855
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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Further Information

Bioactivity:
Gemeprost, an analog of prostaglandin E1, is used for the treatment of obstetric bleeding. It is used to terminate pregnancy up to 24 weeks gestation together with mifepristone.
CAS:
64318-79-2
Formula:
C23H38O5
Molecular Weight:
394.552
Purity:
0.98
SMILES:
CCCCC(C)(C)[C@H](O)C=C[C@H]1[C@H](O)CC(=O)[C@@H]1CCCCC=CC(=O)OC

References

1. Di Carlo C, Savoia F, Morra I, Ferrara C, Sglavo G, Nappi C. Effects of a prolonged, 72 hours, interval between mifepristone and gemeprost in second trimester termination of pregnancy: a retrospective analysis. Gynecol Endocrinol. 2014 Aug;30(8):605-7. doi: 10.3109/09513590.2014.930123. Epub 2014 Jun 6. PubMed PMID: 24905726. 2. La Torre R, Bevilacqua E, D'Ambrosio V, Pasquali G, Aliberti C, Perrone G, Giancotti A. A case of uterine rupture in mid-trimester spontaneous abortion: a complication of gemeprost vaginal administration. Clin Exp Obstet Gynecol. 2014;41(5):599-600. PubMed PMID: 25864271. 3. Domr?se CM, Geipel A, Berg C, Lorenzen H, Gembruch U, Willruth A. Second- and third-trimester termination of pregnancy in women with uterine scar - a retrospective analysis of 111 gemeprost-induced terminations of pregnancy after previous cesarean delivery. Contraception. 2012 Jun;85(6):589-94. doi: 10.1016/j.contraception.2011.10.005. Epub 2011 Nov 12. PubMed PMID: 22079607. 4. Wong KS, Ngai CS, Wong AY, Tang LC, Ho PC. Vaginal misoprostol compared with vaginal gemeprost in termination of second trimester pregnancy. A randomized trial. Contraception. 1998 Oct;58(4):207-10. PubMed PMID: 9866000.