TargetMol

L-4FPG

Product Code:
 
TAR-T21102
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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TAR-T21102-1g1g£104.00
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Further Information

Bioactivity:
L-4FPG inhibits the neutral amino acid transporters ASCT1 and ASCT2. It also shows good brain penetration and potently reduces amphetamine-induced hyperlocomotion.
CAS:
19883-57-9
Formula:
C8H8FNO2
Molecular Weight:
169.155
Purity:
0.9926
SMILES:
N[C@H](C(O)=O)c1ccc(F)cc1

References

1. Li YX, Yang JY, Alcantara M, Abelian G, Kulkarni A, Staubli U, Foster AC. Inhibitors of the Neutral Amino Acid Transporters ASCT1 and ASCT2 Are Effective in In Vivo Models of Schizophrenia and Visual Dysfunction. J Pharmacol Exp Ther. 2018 Nov;367(2):292-301. doi: 10.1124/jpet.118.251116. Epub 2018 Aug 31. PubMed PMID: 30171039.