TargetMol

Amiodarone

Product Code:
 
TAR-T21370
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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TAR-T21370-5mg5mg£850.00
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Further Information

Bioactivity:
Amiodarone is categorized as a class III antiarrhythmic agent and prolongs phase 3 of the cardiac action potential. It also has numerous other effects, including actions that are similar to those of antiarrhythmic classes Ia, II, and IV. Amiodarone chemically resembles thyroxine.
CAS:
1951-25-3
Formula:
C25H29I2NO3
Molecular Weight:
645.32
Purity:
0.98
SMILES:
CCCCc1oc2ccccc2c1C(=O)c1cc(I)c(OCCN(CC)CC)c(I)c1

References

1. Lee HC, Lo HC, Lo DM, Su MY, Hu JR, Wu CC, Chang SN, Dai MS, Tsai CT, Tsai HJ. Amiodarone Induces Overexpression of Similar to Versican b to Repress the EGFR/Gsk3b/Snail Signaling Axis during Cardiac Valve Formation of Zebrafish Embryos. PLoS One. 2015 Dec 9;10(12):e0144751. doi: 10.1371/journal.pone.0144751. eCollection 2015. PubMed PMID: 26650936. 2. Claro JC, Candia R, Rada G, Baraona F, Larrondo F, Letelier LM. Amiodarone versus other pharmacological interventions for prevention of sudden cardiac death. Cochrane Database Syst Rev. 2015 Dec 8;12:CD008093. [Epub ahead of print] Review. PubMed PMID: 26646017. 3. Theodoraki A, Vanderpump MP. Thyrotoxicosis associated with the use of amiodarone: the utility of ultrasound in patient management. Clin Endocrinol (Oxf). 2015 Dec 7. doi: 10.1111/cen.12988. [Epub ahead of print] PubMed PMID: 26642425. 4. Aboul-Fotouh GI, Zickri MB, Metwally HG, Ibrahim IR, Kamar SS, Sakr W. Therapeutic Effect of Adipose Derived Stem Cells versus Atorvastatin on Amiodarone Induced Lung Injury in Male Rat. Int J Stem Cells. 2015 Nov;8(2):170-80. doi: 10.15283/ijsc.2015.8.2.170. PubMed PMID: 26634065; PubMed Central PMCID: PMC4651281.