TargetMol

Mexiletine

Product Code:
 
TAR-T21427
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T21427-5mg5mg£850.00
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TAR-T21427-50mg50mg£1,661.00
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Quantity:
TAR-T21427-100mg100mg£2,079.00
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This product comes from: United States.
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Further Information

Bioactivity:
Mexiletine is a non-selective voltage-gated sodium channel blocker. It is a medicine in the class of IB anti-arrhythmic. Mexiletine may also be used in patients experiencing refractory pain and is effective to treat muscle stiffness resulting from myotonic dystrophy or non-dystrophic myotonias.
CAS:
31828-71-4
Formula:
C11H17NO
Molecular Weight:
179.263
Purity:
0.98
SMILES:
CC(N)COc1c(C)cccc1C

References

1. Catalano A, Carocci A, Sinicropi MS. Mexiletine metabolites: a review. Curr Med Chem. 2015;22(11):1400-13. Review. PubMed PMID: 25723511. 2. Gao Y, Xue X, Hu D, Liu W, Yuan Y, Sun H, Li L, Timothy KW, Zhang L, Li C, Yan GX. Inhibition of late sodium current by mexiletine: a novel pharmotherapeutical approach in timothy syndrome. Circ Arrhythm Electrophysiol. 2013 Jun;6(3):614-22. doi: 10.1161/CIRCEP.113.000092. Epub 2013 Apr 11. Review. PubMed PMID: 23580742. 3. Marmura MJ. Intravenous lidocaine and mexiletine in the management of trigeminal autonomic cephalalgias. Curr Pain Headache Rep. 2010 Apr;14(2):145-50. doi: 10.1007/s11916-010-0098-6. Review. PubMed PMID: 20425204. 4. Ebell MH. Systemic lidocaine or mexiletine for neuropathic pain. Am Fam Physician. 2006 Jul 1;74(1):79. Review. PubMed PMID: 16848381.