TargetMol

L-006235

Product Code:
 
TAR-T21616
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T21616-1mg1mg£103.00
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TAR-T21616-2mg2mg£118.00
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TAR-T21616-5mg5mg£148.00
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TAR-T21616-1mL1 mL * 10 mM (in DMSO)£149.00
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TAR-T21616-10mg10mg£201.00
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TAR-T21616-25mg25mg£334.00
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TAR-T21616-50mg50mg£516.00
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TAR-T21616-100mg100mg£711.00
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Quantity:
TAR-T21616-500mg500mg£1,396.00
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Further Information

Bioactivity:
L 006235 is a potent and reversible inhibitor of cathepsin K with IC50 of 0.25 nM.
CAS:
294623-49-7
Formula:
C24H30N6O2S
Molecular Weight:
466.6
Pathway:
Proteases/Proteasome
Purity:
0.9838
SMILES:
CN1CCN(CC1)c1nc(cs1)-c1ccc(cc1)C(=O)NC1(CCCCC1)C(=O)NCC#N
Target:
Cysteine Protease

References

1. Lena Svelande , Helena Erlandsson-Harris, Leif Astner, et al.Inhibition of cathepsin K reduces bone erosion, cartilage degradation and inflammation evoked by collagen-induced arthritis in mice.Eur J Pharmacol. 2009 Jun 24;613(1-3):155-62.