TargetMol

(E)-AG 556

Product Code:
 
TAR-T21853
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T21853-5mg5mg£108.00
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Quantity:
TAR-T21853-1mL1 mL * 10 mM (in DMSO)£112.00
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TAR-T21853-10mg10mg£135.00
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TAR-T21853-25mg25mg£201.00
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TAR-T21853-50mg50mg£269.00
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Quantity:
TAR-T21853-100mg100mg£366.00
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Quantity:
TAR-T21853-200mg200mg£507.00
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Quantity:
TAR-T21853-500mg500mg£764.00
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Quantity:
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This product comes from: United States.
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Further Information

Bioactivity:
AG 556 is a selective inhibitor of EGFR and blocks LPS-induced TNF-α production.
CAS:
133550-41-1
Formula:
C20H20N2O3
Molecular Weight:
336.38
Pathway:
Angiogenesis; JAK/STAT signaling; Tyrosine Kinase/Adaptors
Purity:
0.98
SMILES:
N#C/C(/C(NCCCCc1ccccc1)=O)=Cc(cc1)cc(O)c1O
Target:
EGFR

References

1. George J, et al. Tyrphostin AG-556 reduces myocardial infarct size and improves cardiac performance in the rat. Exp Mol Pathol. 2003 Jun;74(3):314-8. 2. Gazit A, et al. Tyrphostins. 2. Heterocyclic and alpha-substituted benzylidenemalononitrile tyrphostins as potent inhibitors of EGF receptor and ErbB2/neu tyrosine kinases. J Med Chem. 1991 Jun;34(6):1896-907.