TargetMol

Fipronil

Product Code:
 
TAR-T2196
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T2196-25mg25mg£104.00
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TAR-T2196-1mL1 mL * 10 mM (in DMSO)£107.00
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TAR-T2196-50mg50mg£124.00
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TAR-T2196-100mg100mg£148.00
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TAR-T2196-200mg200mg£181.00
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TAR-T2196-250mg250mg£189.00
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Quantity:
TAR-T2196-500mg500mg£242.00
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This product comes from: United States.
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Further Information

Bioactivity:
Fipronil is a broad-use insecticide that belongs to the phenylpyrazole chemical family. Fipronil is a broad-spectrum insecticide that disrupts the insect central nervous system by blocking GABA-gated chloride channels and glutamate-gated chloride (GluCl) channels, resulting in central nervous system toxicity. This causes hyperexcitation of contaminated insects' nerves and muscles. Specificity of fipronil on insects may come from a better efficacy on GABA receptor, but also because GluCl channels do not exist in mammals.
CAS:
120068-37-3
Formula:
C12H4Cl2F6N4OS
Molecular Weight:
437.14
Pathway:
Neuroscience; Microbiology/Virology; Membrane transporter/Ion channel; Metabolism
Purity:
0.98
SMILES:
Nc1c(c(nn1-c1c(Cl)cc(cc1Cl)C(F)(F)F)C#N)S(=O)C(F)(F)F
Target:
P45; GluCls; GABA Receptor

References

1. Zaluski R, et al. Environ Toxicol Chem. 2015 May;34(5):1062-9. 2. Wang K, Li B, Yu Y, et al. Bacterial Rdl2 dsRNA increased the insecticidal activity of GABAR blockers and allosteric modulators against Plutella xylostella[J]. bioRxiv. 2021