TargetMol

Adenosine Dialdehyde (ADOX)

Product Code:
 
TAR-T22231
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T22231-5mg5mg£111.00
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Quantity:
TAR-T22231-1mL1 mL * 10 mM (in DMSO)£115.00
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TAR-T22231-10mg10mg£122.00
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TAR-T22231-25mg25mg£147.00
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TAR-T22231-50mg50mg£204.00
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Quantity:
TAR-T22231-100mg100mg£270.00
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Quantity:
TAR-T22231-200mg200mg£370.00
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Quantity:
TAR-T22231-500mg500mg£575.00
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Quantity:
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Further Information

Bioactivity:
Adenosine dialdehyde is a purine nucleoside analogue. Adenosine dialdehyde is a potent inhibitor of S-Adenosylhomocysteine hydrolase (SAHH) (Ki=3.3 nM). Adenosine Dialdehyde exhibits potent anti-tumor activity in vivo.
CAS:
34240-05-6
Formula:
C10H11N5O4
Molecular Weight:
265.225
Purity:
0.98
SMILES:
Nc1ncnc2n(cnc12)C(OC(CO)C=O)C=O

References

1. G V Madhavan, et al. Synthesis and antiviral evaluation of 6'-substituted aristeromycins: potential mechanism-based inhibitors of S-adenosylhomocysteine hydrolase. J Med Chem. 2. B Bostrom, et al. Inhibitory effect of adenosine dialdehyde on in situ murine neuroblastoma growth.Cancer Res. 1988 Nov 1;48(21):5933-6.