TargetMol

Doxazosin

Product Code:
 
TAR-T22316
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T22316-1mL1 mL * 10 mM (in DMSO)£111.00
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TAR-T22316-5mg5mg£111.00
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TAR-T22316-10mg10mg£131.00
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TAR-T22316-25mg25mg£173.00
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TAR-T22316-50mg50mg£225.00
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TAR-T22316-100mg100mg£301.00
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TAR-T22316-200mg200mg£417.00
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This product comes from: United States.
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Further Information

Bioactivity:
Doxazosin is a long-lasting inhibitor of α1-adrenoceptors that is widely used to treat benign prostatic hyperplasia and lower urinary tract symptoms.
CAS:
74191-85-8
Formula:
C23H25N5O5
Molecular Weight:
451.483
Pathway:
Neuroscience; GPCR/G Protein
Purity:
0.9985
SMILES:
COc1cc2nc(nc(N)c2cc1OC)N1CCN(CC1)C(=O)C1COc2ccccc2O1
Target:
Adrenergic Receptor

References

1. Miura, Y. and K. Yoshinaga, Doxazosin: a newly developed, selective alpha 1-inhibitor in the management of patients with pheochromocytoma. Am Heart J, 1988. 116(6 Pt 2): p. 1785-9. 2. D'Eletto, R.D. and N.B. Javitt, Effect of doxazosin on cholesterol synthesis in cell culture. J Cardiovasc Pharmacol, 1989. 13 Suppl 2: p. S1-4; discussion S4. 3. Sun, J.A., et al., Stereoselective binding of doxazosin enantiomers to plasma proteins from rats, dogs and humans in vitro. Acta Pharmacol Sin, 2013. 34(12): p. 1568-74.