TargetMol

4-PPBP maleate

Product Code:
 
TAR-T22513
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T22513-5mg5mg£125.00
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Quantity:
TAR-T22513-1mL1 mL * 10 mM (in DMSO)£139.00
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Quantity:
TAR-T22513-10mg10mg£161.00
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TAR-T22513-25mg25mg£254.00
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Quantity:
TAR-T22513-50mg50mg£367.00
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Quantity:
TAR-T22513-100mg100mg£511.00
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Quantity:
TAR-T22513-500mg500mg£1,010.00
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Further Information

Bioactivity:
σ ligand and NR1a/2B NMDA receptors antagonist
CAS:
201216-39-9
Formula:
C25H31NO4
Molecular Weight:
409.526
Pathway:
GPCR/G Protein|Neuroscience
Purity:
0.98
SMILES:
OC(=O)C=CC(O)=O.C(CCc1ccccc1)CN1CCC(CC1)c1ccccc1
Target:
Sigma receptor|NMDAR

References

Whittemore ER, et al. Antagonism of N-methyl-D-aspartate receptors by sigma site ligands: potency, subtype-selectivity and mechanisms of inhibition. J Pharmacol Exp Ther. 1997;282(1):326-338. Tan F, et al. The ? 1 receptor agonist 4-PPBP elicits ERK1/2 phosphorylation in primary neurons: a possible mechanism of neuroprotective action. Neuropharmacology. 2010;59(6):416-424. Takahashi H, et al. PPBP [4-phenyl-1-(4-phenylbutyl) piperidine] decreases brain injury after transient focal ischemia in rats. Stroke. 1996;27(11):2120-2123.