TargetMol

SC79

Product Code:
 
TAR-T2274
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T2274-5mg5mg£112.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T2274-1mL1 mL * 10 mM (in DMSO)£116.00
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Quantity:
TAR-T2274-10mg10mg£140.00
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Quantity:
TAR-T2274-25mg25mg£185.00
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Quantity:
TAR-T2274-50mg50mg£229.00
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Quantity:
TAR-T2274-100mg100mg£334.00
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Quantity:
TAR-T2274-200mg200mg£495.00
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Quantity:
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
SC79, a selective Akt activator, may be used to enhance Akt activity in various pathological and physiological conditions.
CAS:
305834-79-1
Formula:
C17H17ClN2O5
Molecular Weight:
364.78
Pathway:
PI3K/Akt/mTOR signaling; Cytoskeletal Signaling
Purity:
0.98
SMILES:
CCOC(=O)C(C#N)C1C(C(=O)OCC)=C(N)Oc2ccc(Cl)cc12
Target:
Akt

References

1. Jo H, et al. Proc Natl Acad Sci U S A. 2012, 109(26), 10581-10586. 2. So EY, et al. BMC Cancer. 2014, 14, 548. 3. Wang X, Zhu P, Xu S, et al. Antimony,a novel nerve poison, triggers neuronal autophagic death via reactive oxygen species-mediated inhibition of the protein kinase B/mammalian target of rapamycin pathway[J]. The International Journal of Biochemistry & Cell Biology. 2019: 105561. 4. Shi W, Tang Y, Zhi Y, et al. Akt inhibition-dependent downregulation of the Wnt/?-Catenin Signaling pathway contributes to antimony-induced neurotoxicity. Science of the Total Environment. 2020, 737: 140252.