TargetMol

ML-SA1

Product Code:
 
TAR-T23004
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T23004-5mg5mg£108.00
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TAR-T23004-1mL1 mL * 10 mM (in DMSO)£119.00
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TAR-T23004-10mg10mg£130.00
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TAR-T23004-25mg25mg£194.00
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TAR-T23004-50mg50mg£276.00
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TAR-T23004-100mg100mg£379.00
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Quantity:
TAR-T23004-200mg200mg£535.00
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Further Information

Bioactivity:
ML-SA1 is a selective TRPML agonist, inhibits Dengue virus 2 (DENV2) and Zika virus (ZIKV) by promoting lysosomal acidification and protease activity. The IC50 value of ML-SA1 against DENV2 RNA and ZIKV RNA is 8.3 μM and 52.99 μM, respectively[1].
CAS:
332382-54-4
Formula:
C22H22N2O3
Molecular Weight:
362.429
Pathway:
Membrane transporter/Ion channel;
Purity:
0.9928
SMILES:
C[C@@H]1CC(C)(C)N(C(=O)CN2C(=O)c3ccccc3C2=O)c2ccccc12
Target:
TRP/TRPV Channel

References

1. Xia Z, et al. ML-SA1, a selective TRPML agonist, inhibits DENV2 and ZIKV by promoting lysosomal acidification and protease activity. Antiviral Res. 2020;182:104922.