TargetMol

(E/Z)-SIB-1893

Product Code:
 
TAR-T23353
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
❮❯

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CodeSizePrice
TAR-T23353-5mg5mg£124.00
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Quantity:
TAR-T23353-10mg10mg£165.00
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TAR-T23353-25mg25mg£269.00
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Quantity:
TAR-T23353-50mg50mg£385.00
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Quantity:
TAR-T23353-100mg100mg£546.00
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Quantity:
TAR-T23353-500mg500mg£1,099.00
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Quantity:
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This product comes from: United States.
Typical lead time: 10-14 working days.
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Further Information

Bioactivity:
mGlu5 antagonist
CAS:
6266-99-5
Formula:
C14H13N
Molecular Weight:
195.265
Pathway:
Neuroscience|Others
Purity:
0.98
SMILES:
Cc1cccc(C=C/c2ccccc2)n1
Target:
Others|GluR

References

?uszczki JJ, et al. Non-competitive metabotropic glutamate subtype 5 receptor antagonist (SIB-1893) decreases body temperature in rats. Pharmacol Rep. 2005;57(6):795-801. Storto M, et al. Selective blockade of mGlu5 metabotropic glutamate receptors is protective against acetaminophen hepatotoxicity in mice. J Hepatol. 2003;38(2):179-187. Borowicz KK, et al. Influence of SIB 1893, a selective mGluR5 receptor antagonist, on the anticonvulsant activity of conventional antiepileptic drugs in two models of experimental epilepsy. Pol J Pharmacol. 2003;55(5):735-740. O'Leary DM, et al. Selective mGluR5 antagonists MPEP and SIB-1893 decrease NMDA or glutamate-mediated neuronal toxicity through actions that reflect NMDA receptor antagonism. Br J Pharmacol. 2000;131(7):1429-1437.