TargetMol

Tankyrase Inhibitors (TNKS) 49

Product Code:
 
TAR-T23419
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T23419-5mg5mg£222.00
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Quantity:
TAR-T23419-1mL1 mL * 10 mM (in DMSO)£290.00
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TAR-T23419-10mg10mg£335.00
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TAR-T23419-50mg50mg£784.00
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Quantity:
TAR-T23419-100mg100mg£1,195.00
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This product comes from: United States.
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Further Information

Bioactivity:
Tankyrase Inhibitors 49 is an effective, selective, and orally bioavailable inhibitor of tankyrase (IC50: 0.1nM).
CAS:
T23419
Formula:
C24H24N4O3S
Molecular Weight:
448.54
Purity:
0.98
SMILES:
O=C1NC(SCCC(N[C@H]2CC[C@H](OC3=CC=C(C#N)C=C3)CC2)=O)=NC4=CC=CC=C41

References

1. Kelly L M, Yu J C, Boulton C L, et al. CT53518, a novel selective FLT3 antagonist for the treatment of acute myelogenous leukemia (AML)[J]. Cancer cell, 2002, 1(5): 421-432. 2. Ponnurangam S, Standing D, Rangarajan P, et al. Tandutinib inhibits the Akt/mTOR signaling pathway to inhibit colon cancer growth[J]. Molecular cancer therapeutics, 2013, 12(5): 598-609.