TargetMol

5-Et-ddU

Product Code:
 
TAR-T23585
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T23585-5mg5mg£850.00
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Quantity:
TAR-T23585-50mg50mg£1,661.00
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Quantity:
TAR-T23585-100mg100mg£2,079.00
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Further Information

Bioactivity:
5-Et-ddU, Structure-activity relationships of pyrimidine nucleosides as antiviral agents for human immunodeficiency virus type 1 in peripheral blood mononuclear cells.
CAS:
108895-49-4
Formula:
C11H16N2O4
Molecular Weight:
240.259
Purity:
0.98
SMILES:
CCc1cn([C@H]2CC[C@@H](CO)O2)c(=O)[nH]c1=O

References

1. Srivastav NC, Shakya N, Bhavanam S, Agrawal A, Tse C, Desroches N, Kunimoto DY, Kumar R. Antimycobacterial activities of 5-alkyl (or halo)-3'-substituted pyrimidine nucleoside analogs. Bioorg Med Chem Lett. 2012 Jan 15;22(2):1091-4. doi: 10.1016/j.bmcl.2011.11.114. Epub 2011 Dec 4. PubMed PMID: 22178557. 2. Chu CK, Schinazi RF, Ahn MK, Ullas GV, Gu ZP. Structure-activity relationships of pyrimidine nucleosides as antiviral agents for human immunodeficiency virus type 1 in peripheral blood mononuclear cells. J Med Chem. 1989 Mar;32(3):612-7. PubMed PMID: 2918508. 3. Chu CK, Schinazi RF, Arnold BH, Cannon DL, Doboszewski B, Bhadti VB, Gu ZP. Comparative activity of 2',3'-saturated and unsaturated pyrimidine and purine nucleosides against human immunodeficiency virus type 1 in peripheral blood mononuclear cells. Biochem Pharmacol. 1988 Oct 1;37(19):3543-8. PubMed PMID: 3178868. 4. Balzarini J, Baba M, Pauwels R, Herdewijn P, De Clerq E. Anti-retrovirus activity of 3'-fluoro- and 3'-azido-substituted pyrimidine 2',3'-dideoxynucleoside analogues. Biochem Pharmacol. 1988 Jul 15;37(14):2847-56. PubMed PMID: 2840080.