TargetMol

ABC1183

Product Code:
 
TAR-T23601
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T23601-50mg50mgEnquire
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TAR-T23601-5mg5mg£118.00
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TAR-T23601-1mL1 mL * 10 mM (in DMSO)£124.00
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TAR-T23601-10mg10mg£148.00
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TAR-T23601-25mg25mg£230.00
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Further Information

Bioactivity:
ABC1183 is a selective dual inhibitor of the GSK3α/β and CKD9.
CAS:
1042735-18-1
Formula:
C18H14N4OS
Molecular Weight:
334.4
Pathway:
PI3K/Akt/mTOR signaling|Stem Cells|Cell Cycle/Checkpoint
Purity:
0.98
SMILES:
Cc1ccc(Nc2nc(N)c(s2)C(=O)c2ccc(cc2)C#N)cc1
Target:
GSK-3|CDK

References

1. Schrecengost RS, Green CL, Zhuang Y, Keller SN, Smith RA, Maines LW, Smith CD. In Vitro and In Vivo Antitumor and Anti-Inflammatory Capabilities of the Novel GSK3 and CDK9 Inhibitor ABC1183. J Pharmacol Exp Ther. 2018 Apr;365(1):107-116. doi: 10.1124/jpet.117.245738. Epub 2018 Feb 6. PubMed PMID: 29434052.