TargetMol

Adam I-123

Product Code:
 
TAR-T23629
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T23629-5mg5mg£850.00
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This product comes from: United States.
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Further Information

Bioactivity:
Adam I-123 is a radiopharmaceutical containing the serotonin transporter (SERT) ligand, with SERT-binding and radioisotope activities. SERT is a monoamine transporter protein found in the membranes of neurons and platelets.
CAS:
305352-16-3
Formula:
C15H17IN2S
Molecular Weight:
380.28
Purity:
0.98
SMILES:
CN(C)Cc1ccccc1Sc1ccc([123I])cc1N

References

1. Wu CH, Chang CS, Yang YK, Shen LH, Yao WJ. Comparison of brain serotonin transporter using [I-123]-ADAM between obese and non-obese young adults without an eating disorder. PLoS One. 2017 Feb 9;12(2):e0170886. doi: 10.1371/journal.pone.0170886. eCollection 2017. PubMed PMID: 28182708; PubMed Central PMCID: PMC5300236. 2. Huang CI, Yao WJ, Sun YN. New methods for registering long-time I-123 ADAM SPECT image sequences to magnetic resonance images. Nucl Med Commun. 2010 Aug;31(8):734-40. doi: 10.1097/MNM.0b013e32833b7534. PubMed PMID: 20505552. 3. Koch W, Schaaff N, P?pperl G, Mulert C, Juckel G, Reicherzer M, Ehmer-von Geiso C, M?ller HJ, Hegerl U, Tatsch K, Pogarell O. [I-123] ADAM and SPECT in patients with borderline personality disorder and healthy control subjects. J Psychiatry Neurosci. 2007 Jul;32(4):234-40. PubMed PMID: 17653291; PubMed Central PMCID: PMC1911193. 4. Choi SR, Hou C, Oya S, Mu M, Kung MP, Siciliano M, Acton PD, Kung HF. Selective in vitro and in vivo binding of [(125)I]ADAM to serotonin transporters in rat brain. Synapse. 2000 Dec 15;38(4):403-12. PubMed PMID: 11044887.