TargetMol

Adenallene

Product Code:
 
TAR-T23635
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T23635-5mg5mg£850.00
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Quantity:
TAR-T23635-50mg50mg£1,661.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
Quantity:
TAR-T23635-100mg100mg£2,079.00
Special offer! Add £1 to your order to get a TargetMol CCK-8 Kit. Read more here.
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This product comes from: United States.
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Further Information

Bioactivity:
Adenallene inhibits replication and cytopathic effects of HIV in vitro.
CAS:
114987-18-7
Formula:
C9H9N5O
Molecular Weight:
203.205
Purity:
0.98
SMILES:
Nc1ncnc2n(C=C=CCO)cnc12

References

1. Egron D, P?rigaud C, Gosselin G, Aubertin AM, Gatanaga H, Mitsuya H, Zemlicka J, Imbach JL. Increase of the adenallene anti-HIV activity in cell culture using its bis(tBuSATE) phosphotriester derivative. Bioorg Med Chem Lett. 2002 Jan 21;12(2):265-6. PubMed PMID: 11755368. 2. Winter H, Maeda Y, Uchida H, Mitsuya H, Zemlicka J. Phosphodiester amidates of unsaturated nucleoside analogues: synthesis and anti-HIV activity. J Med Chem. 1997 Jul 4;40(14):2191-5. PubMed PMID: 9216838. 3. Winter H, Maeda Y, Mitsuya H, Zemlicka J. Phosphodiester amidates of allenic nucleoside analogues: anti-HIV activity and possible mechanism of action. J Med Chem. 1996 Aug 16;39(17):3300-6. PubMed PMID: 8765513. 4. Jones BC, Silverton JV, Simons C, Megati S, Nishimura H, Maeda Y, Mitsuya H, Zemlicka J. Synthesis, absolute configuration, and enantioselectivity of antiretroviral effect of (R)-(-)- and (S)-(+)-cytallene. Lipase-catalyzed enantioselective acylations of (+/-)-N4-acylcytallenes. J Med Chem. 1995 Apr 14;38(8):1397-405. PubMed PMID: 7731024.