TargetMol

Zindoxifene

Product Code:
 
TAR-T23647
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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CodeSizePrice
TAR-T23647-5mg5mg£850.00
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TAR-T23647-50mg50mg£1,661.00
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Quantity:
TAR-T23647-100mg100mg£2,079.00
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This product comes from: United States.
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Further Information

Bioactivity:
In rats, Zindoxifene has been found to have anti-neoplastic activity in androgen-dependent prostatic tumors.
CAS:
86111-26-4
Formula:
C21H21NO4
Molecular Weight:
351.402
Purity:
0.98
SMILES:
CCn1c(c(C)c2cc(OC(C)=O)ccc12)-c1ccc(OC(C)=O)cc1

References

1. Stein RC, Dowsett M, Cunningham DC, Davenport J, Ford HT, Gazet JC, von Angerer E, Coombes RC. Phase I/II study of the anti-oestrogen zindoxifene (D16726) in the treatment of advanced breast cancer. A Cancer Research Campaign Phase I/II Clinical Trials Committee study. Br J Cancer. 1990 Mar;61(3):451-3. PubMed PMID: 2328214; PubMed Central PMCID: PMC1971274. 2. Schneider MR, Schiller CD, Humm A, von Angerer E. Effect of zindoxifene on experimental prostatic tumours of the rat. J Cancer Res Clin Oncol. 1991;117(1):33-6. PubMed PMID: 1997466. 3. von Angerer E, Prekajac J, Berger M. The inhibitory effect of 5-acetoxy-2-(4-acetoxyphenyl)-1-ethyl-3-methylindole (D 16726) on estrogen-dependent mammary tumors. Eur J Cancer Clin Oncol. 1985 Apr;21(4):531-7. PubMed PMID: 3924626. 4. von Angerer E, Birnb?ck H, Kager M, Maucher A. The effect of a combination of zindoxifene and cisplatin on Dunning R3327-G prostatic carcinomas of the rat. J Cancer Res Clin Oncol. 1992;118(5):339-43. PubMed PMID: 1583065.