TargetMol

AH 22921

Product Code:
 
TAR-T23670
Product Group:
 
Inhibitors and Activators
Supplier:
 
TargetMol
Regulatory Status:
 
RUO
Shipping:
 
cool pack
Storage:
 
-20℃
1 / 1
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TAR-T23670-5mg5mg£850.00
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Further Information

Bioactivity:
AH 22921 is an antagonist of thromboxane A2.
CAS:
123122-56-5
Formula:
C29H35NO5
Molecular Weight:
477.601
Purity:
0.98
SMILES:
OC(=O)CCCC=C/C[C@H]1[C@H](CC(=O)[C@@H]1N1CCOCC1)OCc1ccc(cc1)-c1ccccc1

References

1. Sharif NA, Xu SX. Pharmacological characterization and identification of EP3 prostanoid receptor binding sites in hamster uterus homogenates. J Pharm Pharmacol. 2004 Feb;56(2):197-203. PubMed PMID: 15005878. 2. Crider JY, Griffin BW, Sharif NA. Endogenous EP4 prostaglandin receptors coupled positively to adenylyl cyclase in Chinese hamster ovary cells: pharmacological characterization. Prostaglandins Leukot Essent Fatty Acids. 2000 Jan;62(1):21-6. PubMed PMID: 10765975. 3. Coleman RA, Mallett A, Sheldrick RL. EP4-receptors and cyclic AMP in pig venous smooth muscle: evidence with agonists and the EP4-antagonist, AH22921. Adv Prostaglandin Thromboxane Leukot Res. 1995;23:241-6. PubMed PMID: 7732844. 4. Boura AL, Gude NM, King RG, Mak KK, Walters WA. Characterization of thromboxane A2 receptors in the human fetal placental vessels and umbilical vein. Clin Exp Pharmacol Physiol. 1986 Jan;13(1):83-6. PubMed PMID: 3011331.